Sildenafil Citrate: What You Need to Know

When working with Sildenafil Citrate, a short‑acting PDE5 inhibitor used to treat erectile dysfunction. Also known as Viagra, it works by relaxing blood vessels in the penis to improve blood flow.

Understanding erectile dysfunction, the inability to achieve or maintain an erection sufficient for sexual activity is essential because it drives the need for agents like sildenafil. The condition affects millions worldwide and often stems from vascular, neurological, or psychological factors. PDE5 inhibitors, a drug class that blocks the phosphodiesterase‑5 enzyme—including sildenafil, tadalafil, and vardenafil—are the first‑line therapy for most cases.

How It Works, Who Should Use It, and What to Watch For

Sildenafil citrate requires a prescription, which ensures a doctor checks for contraindications such as nitrate medication or severe heart disease. Typical dosing starts at 50 mg about an hour before sexual activity, with adjustments up to 100 mg based on efficacy and tolerance. Timing, food intake, and individual metabolism can change how quickly the drug takes effect.

Side effects are usually mild—headache, flushing, or upset stomach—but rare reactions like vision changes or priapism need immediate medical attention. Interactions with alcohol, grapefruit juice, or certain antibiotics can raise blood levels, so open communication with your healthcare provider is key.

Beyond treating erectile dysfunction, sildenafil is approved for pulmonary arterial hypertension under a different brand name. This illustrates the broader therapeutic potential of PDE5 inhibition in improving blood vessel function.

Below you’ll find a curated set of articles that dive into real‑world scenarios: dosage calculators, safety checklists, comparisons with other PDE5 inhibitors, and tips for getting the best results without compromising health. Keep reading to see how these insights can help you make informed decisions about using sildenafil citrate safely and effectively.